Gender: Feminine
Origin: Latin
Meaning: “queen.”
Eng (reh-JEE-nah); Old Eng (reh-JYE-nah); It (ray-JEE-nah); Sp (rey-HEE-nah); Pol/Russ (reh-GHEE-nah).
The name is of late Latin origins and in the Middle Ages, was popularized by a French saint.
Saint Reine/Regina was a virgin martyr whose cult was especially popular in the area of Autun France. Her feast day is September 7th.
In Medieval England, the name was used as a epithet for the Virgin Mary, referencing her as Queen of Heaven. The name fell out of usage after the Reformation and was revived in the 19th-century.
Other famous Reginas include a concubine to Emperor Charlemagne (708); she was the mother of Drogo and Hugh.
Currently, the name is borne by Regina Spektor (b.1980).
Other forms include:
Regina (Croatian/Dutch/English/German/Italian/Lithuanian/Polish/Romansch/Swedish)
Regína (Czech/Hungarian/Slovak)
Regine (Danish/German/Norwegian)
Regiina (Estonian)
Reine (French: archaic)
Régine (French)
Gina (Italian/English)
Reggina (Italian)
Reginella (Italian)
Reginetta (Italian)
Reina/Reyna (Spanish/Estonian)
An obscure Italian male form is Regino.
Source
Regina is very popular in Mexico City. I know at least five under the age of ten and several baby boys who, had they been girls, would have been named Regina.
This name is quite common in Portugal as well, but more on middle-aged women. We pronounce it [rə-ZHEE-nuh].
I would say in the States its more common on older women as well. I only know one child with this name.