Gender: Masculine
Origin: Italian
Meaning: “little saint; holy card.”
(sahn-TEE-no)
The name comes directly from the Italian word santo meaning “saint” and is also used as word in Italian to describe small images of saints, known in English as a holy card or a prayer card.
The name was always very common among Italian-Americans, most of whom were anglicized as Sonny.
Currently, Santino is the 652nd most popular male name in the United States, (2010).
Santo is also used as a given name in Italy.
Feminine forms include: Santa, Santina and Santuzza.
Source